Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 14/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.61 |
| ▸ | CCND3 | P30281 | 13/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28936880 | 1.00 | CDK4 (0.61) | CDK4HDAC6CCND3JAK2SYK | |
| SCHEMBL28707536 | 0.99 | CDK4 (0.61) | CDK4HDAC6CCND3JAK2SYK | |
| SCHEMBL28936878 | 0.91 | HDAC6 (0.73) | CDK4HDAC6CCND3JAK2HDAC1 | |
| SCHEMBL29400653 | 0.91 | HDAC6 (0.73) | CDK4HDAC6CCND3JAK2HDAC1 | |
| SCHEMBL29402179 | 0.90 | HDAC6 (0.74) | CDK4HDAC6CCND3JAK2HDAC1 | |
| SCHEMBL28714824 | 0.90 | HDAC6 (0.74) | CDK4HDAC6CCND3JAK2HDAC1 | |
| SCHEMBL28714811 | 0.86 | HDAC6 (0.58) | CDK4HDAC6CCND3JAK2SYK | |
| SCHEMBL28716656 | 0.85 | CDK4 (0.83) | CDK4HDAC6CCND3JAK2SYK | |
| SCHEMBL28716651 | 0.85 | HDAC6 (0.59) | CDK4HDAC6CCND3JAK2SYK | |
| SCHEMBL28714810 | 0.83 | JAK2 (0.48) | CDK4HDAC6CCND3JAK2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105958-B | Hydroximic acid-containing 2-phenylamino pyrimidine derivatives and application thereof | 郑州大学第一附属医院 | 2022-11-22 | — | — | CN | disclosed |