Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.72 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.71 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924271 | 1.00 | TLR8 (0.72) | TLR8TLR7KCNH2APP | |
| SCHEMBL19924270 | 1.00 | TLR8 (0.72) | TLR8TLR7KCNH2APP | |
| SCHEMBL19935595 | 0.87 | TLR8 (0.54) | TLR8TLR7KCNH2APP | |
| SCHEMBL19924250 | 0.85 | KCNH2 (0.73) | TLR8TLR7KCNH2 | |
| SCHEMBL19924248 | 0.85 | KCNH2 (0.73) | TLR8TLR7KCNH2 | |
| SCHEMBL30076107 | 0.85 | KCNH2 (0.73) | TLR8TLR7KCNH2 | |
| SCHEMBL18109529 | 0.84 | TLR8 (0.74) | TLR8TLR7KCNH2 | |
| SCHEMBL18109528 | 0.84 | TLR8 (0.74) | TLR8TLR7KCNH2 | |
| SCHEMBL18109290 | 0.84 | TLR8 (1.00) | TLR8TLR7KCNH2APP | |
| SCHEMBL18109543 | 0.84 | TLR8 (1.00) | TLR8TLR7KCNH2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109923106-B | toll-like receptor modulator compounds | 吉利德科学公司 | 2022-09-13 | — | — | CN | disclosed |