Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.39 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924186 | 1.00 | FLT3 (0.39) | FLT3TYRO3MERTKGAS6BCDIN3D | |
| SCHEMBL19924184 | 1.00 | FLT3 (0.39) | FLT3TYRO3MERTKGAS6BCDIN3D | |
| SCHEMBL19924272 | 0.92 | TSHR (0.40) | FLT3TYRO3MERTKGAS6BCDIN3D | |
| SCHEMBL30076198 | 0.92 | TSHR (0.40) | FLT3TYRO3MERTKGAS6BCDIN3D | |
| SCHEMBL19924273 | 0.92 | TSHR (0.40) | FLT3TYRO3MERTKGAS6BCDIN3D | |
| SCHEMBL19924222 | 0.89 | CYP1A2 (0.47) | HSD17B10CYP1A2CYP3A4CYP2C19TSHR | |
| SCHEMBL19924221 | 0.89 | CYP1A2 (0.47) | HSD17B10CYP1A2CYP3A4CYP2C19TSHR | |
| SCHEMBL19924194 | 0.87 | KDM4C (0.43) | FLT3TYRO3MERTKGAS6BCDIN3D | |
| SCHEMBL19924196 | 0.87 | KDM4C (0.43) | FLT3TYRO3MERTKGAS6BCDIN3D | |
| SCHEMBL18109427 | 0.86 | TLR8 (0.46) | FLT3TYRO3MERTKGAS6BCDIN3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109923106-B | toll-like receptor modulator compounds | 吉利德科学公司 | 2022-09-13 | — | — | CN | disclosed |