Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423267 | 0.89 | OPRL1 (0.60) | OPRL1OPRM1 | |
| SCHEMBL24157288 | 0.80 | ESR1 (0.58) | ALDH1A1L3MBTL1OPRM1ESR1ESR2 | |
| SCHEMBL30078304 | 0.80 | ESR1 (0.58) | ALDH1A1L3MBTL1OPRM1ESR1ESR2 | |
| SCHEMBL30877902 | 0.80 | ESR1 (0.58) | ALDH1A1L3MBTL1OPRM1ESR1ESR2 | |
| SCHEMBL54982 | 0.80 | ESR1 (0.58) | ALDH1A1L3MBTL1OPRM1ESR1ESR2 | |
| SCHEMBL28378542 | 0.80 | ESR1 (0.58) | ALDH1A1L3MBTL1OPRM1ESR1ESR2 | |
| SCHEMBL30877914 | 0.80 | ESR1 (0.58) | ALDH1A1L3MBTL1OPRM1ESR1ESR2 | |
| Hydrogen Peroxide SCHEMBL2349581 | 0.78 | ESR1 (0.62) | ALDH1A1L3MBTL1OPRM1ESR1ESR2 | |
| SCHEMBL1515174 | 0.78 | ESR1 (0.56) | ALDH1A1L3MBTL1OPRM1ESR1ESR2 | |
| Ammonia Solution, Strong SCHEMBL7989528 | 0.78 | ESR1 (0.56) | ALDH1A1L3MBTL1OPRM1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490708-A | Sulfonamide macrocyclic derivatives, and preparation method and application thereof | 苏州亚盛药业有限公司 | 2022-12-20 | — | — | CN | disclosed |