Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407643 | 1.00 | NR1H2 (0.50) | NR1H2TACR1MEN1KMT2ACHRM2 | |
| SCHEMBL7407645 | 1.00 | NR1H2 (0.50) | NR1H2TACR1MEN1KMT2ACHRM2 | |
| SCHEMBL29770677 | 1.00 | NR1H2 (0.50) | NR1H2TACR1MEN1KMT2ACHRM2 | |
| SCHEMBL7407641 | 1.00 | NR1H2 (0.50) | NR1H2TACR1MEN1KMT2ACHRM2 | |
| SCHEMBL30636951 | 1.00 | NR1H2 (0.50) | NR1H2TACR1MEN1KMT2ACHRM2 | |
| SCHEMBL35211182 | 0.88 | NR1H2 (0.43) | NR1H2TACR1CHRM2CHRM1CHRM3 | |
| SCHEMBL19860426 | 0.86 | NR1H2 (0.49) | NR1H2TACR1MEN1KMT2ACHRM2 | |
| SCHEMBL31218882 | 0.86 | NR1H2 (0.41) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL30636995 | 0.84 | NR1H2 (0.49) | NR1H2TACR1MEN1KMT2ACHRM2 | |
| SCHEMBL114606 | 0.82 | NR1H2 (0.44) | NR1H2CHRM2CHRM1CHRM3USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118894-A | TRPV4 receptor ligands | 犹他大学研究基金会 | 2024-12-13 | — | — | CN | disclosed |
| CN-115052478-A | TRPV4 receptor ligands | 犹他大学研究基金会 | 2022-09-13 | — | — | CN | disclosed |