SCHEMBL30079746

SCHEMBL30079746

[2H]C([2H])([2H])n1ncc(-c2ccnc(N)c2OC)n1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24776721 0.90 TYK2 (0.35) USP7
SCHEMBL29947295 0.90 TYK2 (0.35) USP7
SCHEMBL30079393 0.84 CYP17A1 (0.31)
SCHEMBL24776723 0.76 PIK3CA (0.34)
SCHEMBL24823062 0.75 SCN9A (0.34)
SCHEMBL24822834 0.73 TYK2 (0.35)
SCHEMBL31280404 0.73 TYK2 (0.33)
SCHEMBL30079457 0.73 TYK2 (0.35)
SCHEMBL22635692 0.71 TYK2 (0.39)
SCHEMBL24824810 0.70 TTK (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4337655-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS Bristol-Myers Squibb Company (US) 2024-03-20 EP disclosed
WO-2022241171-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2022-11-17 WO disclosed