Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 3/20 | 0.69 |
| ▸ | ABL1 | P00519 | 10/20 | 0.66 |
| ▸ | DDR2 | Q16832 | 14/20 | 0.65 |
| ▸ | DDR1 | Q08345 | 13/20 | 0.65 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.65 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.65 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.65 |
| ▸ | RET | P07949 | 3/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | BCR | P11274 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2965773 | 1.00 | KIT (0.69) | KITABL1DDR2DDR1NTRK1 | |
| SCHEMBL22299749 | 0.88 | KIT (0.65) | KITABL1DDR2DDR1NTRK1 | |
| SCHEMBL22025455 | 0.86 | DDR2 (0.65) | KITABL1DDR2DDR1NTRK1 | |
| SCHEMBL2976022 | 0.86 | KIT (0.68) | KITABL1DDR2DDR1NTRK1 | |
| SCHEMBL16755297 | 0.85 | KIT (0.70) | KITABL1DDR2SRC | |
| SCHEMBL22772380 | 0.84 | DDR1 (0.67) | KITABL1DDR2DDR1NTRK1 | |
| SCHEMBL2969932 | 0.84 | DDR1 (0.84) | KITABL1DDR2DDR1NTRK1 | |
| SCHEMBL2966026 | 0.84 | DDR2 (0.72) | KITABL1DDR2DDR1NTRK1 | |
| SCHEMBL2964721 | 0.83 | DDR1 (0.85) | KITABL1DDR2DDR1NTRK1 | |
| SCHEMBL2973073 | 0.83 | KIT (0.77) | KITABL1DDR2DDR1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246327-B1 | 3-ACETYLENYL-PYRAZOLE-PYRIMIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USES THEREOF | SI CHUAN UNIV (CN) | 2022-11-23 | — | — | EP | disclosed |