Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28894673 | 1.00 | PIK3CA (0.53) | PIK3CAMAPTTSHRHSD17B10MAPK1 | |
| SCHEMBL30085611 | 0.91 | PIK3CA (0.52) | PIK3CAMAPTTSHRHSD17B10MAPK1 | |
| SCHEMBL28894946 | 0.91 | PIK3CA (0.52) | PIK3CAMAPTTSHRHSD17B10MAPK1 | |
| SCHEMBL28895016 | 0.90 | PIK3CA (0.50) | PIK3CAMAPTTSHRHSD17B10MAPK1 | |
| SCHEMBL30085461 | 0.90 | PIK3CA (0.50) | PIK3CAMAPTTSHRHSD17B10MAPK1 | |
| SCHEMBL30085378 | 0.90 | MAPT (0.52) | PIK3CAMAPTTSHRHSD17B10MAPK1 | |
| SCHEMBL28894764 | 0.90 | MAPT (0.52) | PIK3CAMAPTTSHRHSD17B10MAPK1 | |
| SCHEMBL28894548 | 0.88 | PIK3CA (0.48) | PIK3CAMAPTTSHRHSD17B10MAPK1 | |
| SCHEMBL30085624 | 0.88 | HPGD (0.59) | PIK3CAMAPTTSHRHSD17B10MAPK1 | |
| SCHEMBL28894859 | 0.88 | HPGD (0.59) | PIK3CAMAPTTSHRHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397818-A | Aminopyrimidine derivatives and their use as modulators of arene receptors | 东亚ST株式会社 | 2022-11-25 | — | — | CN | claimed |
| CN-115397818-A | Aminopyrimidine derivatives and their use as modulators of arene receptors | 东亚ST株式会社 | 2022-11-25 | — | — | CN | disclosed |