Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27176268 | 1.00 | NPSR1 (0.67) | NPSR1SMN1; SMN2NPC1NAMPTHSD17B10 | |
| SCHEMBL10822161 | 0.80 | KMT2A (0.71) | SMN1; SMN2NPC1NAMPTHSD17B10KDM4E | |
| SCHEMBL10061968 | 0.78 | KDM4E (0.66) | SMN1; SMN2NPC1NAMPTKDM4EMEN1 | |
| SCHEMBL10045194 | 0.78 | HDAC3 (0.52) | SMN1; SMN2KDM4ELMNAPOLB | |
| SCHEMBL34468767 | 0.78 | KDM4E (0.67) | NPSR1SMN1; SMN2NPC1NAMPTHSD17B10 | |
| SCHEMBL1775216 | 0.77 | SMN1; SMN2 (0.82) | SMN1; SMN2NPC1NAMPTKDM4EMEN1 | |
| SCHEMBL8594130 | 0.77 | HDAC3 (0.60) | SMN1; SMN2NPC1TSHRLMNAPOLB | |
| SCHEMBL10820783 | 0.77 | MEN1 (0.67) | NAMPTHSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL10045224 | 0.76 | KDM4E (0.53) | SMN1; SMN2KDM4ELMNAPOLB | |
| SCHEMBL28378029 | 0.76 | HDAC3 (0.58) | SMN1; SMN2NPC1KDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4341386-A2 | METHODS FOR THE EXPANSION OF HUMAN GRANULOCYTEMACROPHAGE PROGENITORS AND APPLICATIONS THEREOF | University of Southern California (US) | 2024-03-27 | — | — | EP | disclosed |
| CN-117751182-A | Method for amplifying human granulocyte-macrophage progenitor cells and application thereof | 南加利福尼亚大学 | 2024-03-22 | — | — | CN | disclosed |
| WO-2022245977-A2 | METHODS FOR THE EXPANSION OF HUMAN GRANULOCYTEMACROPHAGE PROGENITORS AND APPLICATIONS THEREOF | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2022-11-24 | — | — | WO | disclosed |