Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23665909 | 1.00 | KDM4E (0.54) | KDM4EHSD17B10GAAMAPK1HPGD | |
| SCHEMBL23649529 | 0.91 | KDM4E (0.51) | KDM4EHSD17B10GAAMAPK1HPGD | |
| SCHEMBL29546975 | 0.91 | KDM4E (0.51) | KDM4EHSD17B10GAAMAPK1HPGD | |
| SCHEMBL23649069 | 0.89 | KDM4E (0.52) | KDM4EHSD17B10GAAMAPK1HPGD | |
| SCHEMBL30041218 | 0.89 | KDM4E (0.52) | KDM4EHSD17B10GAAMAPK1HPGD | |
| SCHEMBL23773716 | 0.89 | RAD52 (0.56) | KDM4EHSD17B10GAAMAPK1HPGD | |
| SCHEMBL31731628 | 0.89 | RAD52 (0.56) | KDM4EHSD17B10GAAMAPK1HPGD | |
| SCHEMBL25270148 | 0.89 | KDM4E (0.48) | KDM4EHSD17B10GAAMAPK1HPGD | |
| SCHEMBL31731482 | 0.89 | PIKFYVE (0.59) | KDM4EHSD17B10GAAMAPK1HPGD | |
| SCHEMBL23649076 | 0.89 | PIKFYVE (0.59) | KDM4EHSD17B10GAAMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4103281-A1 | PIKFYVE KINASE INHIBITORS | Acurastem Inc. (US) | 2022-12-21 | — | — | EP | disclosed |