Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19029928 | 1.00 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL19029913 | 0.88 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL30090056 | 0.88 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL19046056 | 0.87 | IRAK4 (0.44) | IRAK4 | |
| SCHEMBL19029878 | 0.85 | IRAK4 (0.53) | IRAK4 | |
| SCHEMBL19030407 | 0.85 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL29935373 | 0.85 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL19030515 | 0.85 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL19044655 | 0.85 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL19029881 | 0.84 | IRAK4 (0.54) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480101-B | IRAK4 kinase inhibitor, preparation and application thereof | 中国科学院上海药物研究所 | 2022-11-25 | — | — | CN | disclosed |