Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 2/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2029799 | 1.00 | SMO (0.40) | SMOADRA1AKAT2BBRD9PRCP | |
| SCHEMBL302292 | 0.93 | SMO (0.43) | SMOPRCPSCN2A | |
| SCHEMBL1921989 | 0.92 | SMO (0.42) | SMOPRCPSCN2ASSTR3 | |
| SCHEMBL1922090 | 0.92 | SMO (0.42) | SMOPRCPSCN2ASSTR3 | |
| SCHEMBL302505 | 0.92 | SMO (0.43) | SMOKAT2BBRD9SCN2A | |
| SCHEMBL1922432 | 0.91 | SMO (0.41) | SMOKAT2BBRD9PRCPSCN2A | |
| SCHEMBL1923378 | 0.89 | SMO (0.43) | SMOPRCPSCN2A | |
| SCHEMBL305512 | 0.89 | SMO (0.44) | SMOSCN2A | |
| SCHEMBL1921424 | 0.88 | SMO (0.40) | SMOPRCPSCN2A | |
| SCHEMBL304396 | 0.88 | SMO (0.40) | SMOSSTR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115414480-A | Dianhydrogalactitol in combination with radiation for treatment of non-small cell lung cancer and glioblastoma multiforme | 德玛医药 | 2022-12-02 | — | — | CN | disclosed |