Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 5/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.31 |
| ▸ | CDC25B | P30305 | 4/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.31 |
| ▸ | CDC25A | P30304 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30090999 | 0.94 | TMPRSS2 (0.39) | TMPRSS2GLSCTSSCTSKCTSL | |
| SCHEMBL30090946 | 0.91 | TMPRSS2 (0.35) | TMPRSS2CTSSCTSKMEN1KMT2A | |
| SCHEMBL25909955 | 0.91 | TMPRSS2 (0.40) | TMPRSS2GLSCTSSCTSKCTSL | |
| SCHEMBL24917331 | 0.91 | TMPRSS2 (0.44) | TMPRSS2GLSCTSSCTSKCTSL | |
| SCHEMBL25922652 | 0.87 | TMPRSS2 (0.39) | TMPRSS2GLSCTSSCTSKCTSL | |
| SCHEMBL30090993 | 0.86 | TMPRSS2 (0.48) | TMPRSS2 | |
| SCHEMBL30973736 | 0.86 | TMPRSS2 (0.38) | TMPRSS2GLSCTSSCTSKCTSL | |
| SCHEMBL30973764 | 0.86 | TMPRSS2 (0.38) | TMPRSS2GLSCTSSCTSKCTSL | |
| SCHEMBL30973779 | 0.85 | TMPRSS2 (0.38) | TMPRSS2GLSPTPN1CDC25BPTPN2 | |
| SCHEMBL27413367 | 0.85 | TMPRSS2 (0.38) | TMPRSS2GLSPTPN1CDC25BPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118139868-A | Orally bioavailable nucleoside analogs | 维纳拓尔斯制药公司 | 2024-06-04 | — | — | CN | disclosed |
| EP-4355755-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | Venatorx Pharmaceuticals, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022265964-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. (US) | 2022-12-22 | — | — | WO | disclosed |