SCHEMBL30091304

SCHEMBL30091304

C[C@@H](O)[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)C(C)(C)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@](C)(F)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccc(-c2ccccc2)cc1)C(=O)N[C@@H](Cc1ccc(-c2ccccc2)cc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.55
▸ SCTR P47872 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30091176 0.96 GLP1R (0.58) GLP1RSCTR
SCHEMBL30091379 0.96 GLP1R (0.58) GLP1RSCTR
SCHEMBL30091292 0.95 GLP1R (0.55) GLP1RSCTR
SCHEMBL30091171 0.95 GLP1R (0.58) GLP1RSCTR
SCHEMBL30091122 0.95 GLP1R (0.56) GLP1RSCTR
SCHEMBL30091165 0.94 GLP1R (0.55) GLP1RSCTR
SCHEMBL30091278 0.94 GLP1R (0.55) GLP1RSCTR
SCHEMBL30091352 0.94 GLP1R (0.57) GLP1RSCTR
SCHEMBL30091298 0.93 GLP1R (0.56) GLP1RSCTR
SCHEMBL30091268 0.93 GLP1R (0.60) GLP1RSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254186-A1 GLP-1 Receptor Agonists Having Improved Pharmacological and Drug Delivery Properties DARBIX LLC 2024-08-01 — — US disclosed
US-20230015478-A1 GLP-1 RECEPTOR AGONISTS HAVING IMPROVED PHARMACOLOGICAL AND DRUG DELIVERY PROPERTIES RESOLUTE BIO INC (US) 2023-01-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230015478-A1 GLP-1 RECEPTOR AGONISTS HAVING IMPROVED PHARMACOLOGICAL AND DRUG DELIVERY PROPERTIES GLP1R, GIPR, IAPP GLP1R 1/4885SCTR 9/4885
US-20240254186-A1 GLP-1 Receptor Agonists Having Improved Pharmacological and Drug Delivery Properties GLP1R, GIPR, IAPP GLP1R 1/4885SCTR 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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