Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23412465 | 1.00 | KMT2A (0.78) | KMT2AHPGDALDH1A1NPC1CYP1A2 | |
| SCHEMBL17354444 | 0.91 | KMT2A (0.72) | KMT2AHPGDALDH1A1NPC1CYP1A2 | |
| SCHEMBL29687327 | 0.86 | HPGD (1.00) | KMT2AHPGDALDH1A1NPC1CYP1A2 | |
| SCHEMBL743611 | 0.86 | HPGD (1.00) | KMT2AHPGDALDH1A1NPC1CYP1A2 | |
| SCHEMBL30678539 | 0.86 | HPGD (1.00) | KMT2AHPGDALDH1A1NPC1CYP1A2 | |
| SCHEMBL24494843 | 0.85 | KMT2A (0.73) | KMT2AHPGDALDH1A1NPC1CYP1A2 | |
| SCHEMBL24494867 | 0.84 | KMT2A (0.78) | KMT2AHPGDALDH1A1NPC1CYP1A2 | |
| SCHEMBL18719834 | 0.83 | KMT2A (0.74) | KMT2AHPGDALDH1A1NPC1CYP1A2 | |
| SCHEMBL13162949 | 0.80 | MAPT (0.77) | KMT2AHPGDALDH1A1NPC1CYP1A2 | |
| SCHEMBL13162950 | 0.80 | MAPT (0.77) | KMT2AHPGDALDH1A1NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397806-A | Aryl and heteroaryl compounds and their therapeutic use in conditions associated with altered activity of galactocerebrosidase | 增益治疗股份有限公司 | 2022-11-25 | — | — | CN | disclosed |