Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 7/20 | 0.77 |
| ▸ | CRACR2A | Q9BSW2 | 10/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670240 | 1.00 | ORAI1 (0.77) | ORAI1CRACR2ASMN1; SMN2HTTLMNA | |
| SCHEMBL1889737 | 0.87 | ORAI1 (1.00) | ORAI1CRACR2ASMN1; SMN2HTTLMNA | |
| SCHEMBL12661309 | 0.86 | ORAI1 (0.81) | ORAI1CRACR2ASMN1; SMN2HTTLMNA | |
| SCHEMBL1668577 | 0.86 | ORAI1 (1.00) | ORAI1CRACR2A | |
| SCHEMBL1668844 | 0.85 | ORAI1 (1.00) | ORAI1CRACR2A | |
| SCHEMBL31174912 | 0.83 | ORAI1 (0.91) | ORAI1CRACR2ASMN1; SMN2HTTLMNA | |
| SCHEMBL1667864 | 0.80 | ORAI1 (0.60) | ORAI1CRACR2A | |
| SCHEMBL1668146 | 0.79 | RXFP1 (0.59) | ORAI1CRACR2A | |
| SCHEMBL30096524 | 0.79 | ORAI1 (0.71) | ORAI1CRACR2A | |
| SCHEMBL1669977 | 0.79 | ORAI1 (0.71) | ORAI1CRACR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4465988-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATION INJURY IN THE LUNGS | Calcimedica, Inc. (US) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023141523-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATION INJURY IN THE LUNGS | CALCIMEDICA, INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| EP-4121089-A1 | METHODS AND COMPOSITIONS FOR TREATING ACUTE LUNG INJURY AND ACUTE RESPIRATORY DISTRESS SYNDROME | Calcimedica, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |