⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6307027 | 1.00 | — | — | |
| SCHEMBL191846 | 0.81 | — | — | |
| SCHEMBL29479539 | 0.81 | — | — | |
| SCHEMBL28287558 | 0.81 | CYP3A4 (0.34) | — | |
| SCHEMBL1661352 | 0.79 | — | — | |
| SCHEMBL13893598 | 0.79 | — | — | |
| SCHEMBL29501319 | 0.79 | — | — | |
| Ethoxycarbonyl Group SCHEMBL27518121 | 0.77 | MAPT (0.31) | — | |
| Hydrochloric Acid SCHEMBL3615862 | 0.77 | GAA (0.46) | — | |
| Hydrochloric Acid SCHEMBL28182269 | 0.77 | GAA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118510776-A | Five-membered ring-containing derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-118344289-A | Phenyl substituted heteroaryl compound, and pharmaceutical composition, preparation method and application thereof | 上海美悦生物科技发展有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| WO-2023134765-A1 | FIVE-MEMBERED-RING-CONTAINING DERIVATIVES, PREPARATION METHOD THEREFOR, AND USES THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |
| CN-116444493-A | Derivative containing double parallel rings, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-07-18 | — | — | CN | disclosed |
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| EP-4096668-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |