Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 8/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 7/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27410555 | 1.00 | PRMT1 (0.41) | PRMT1EGFRMAPK1LMNACYP1A2 | |
| SCHEMBL27409830 | 0.85 | RPS6KB1 (0.48) | AURKARPS6KB1AURKB | |
| SCHEMBL30097217 | 0.85 | RPS6KB1 (0.48) | AURKARPS6KB1AURKB | |
| SCHEMBL27409232 | 0.83 | PRMT1 (0.39) | PRMT1EGFRMAPK1LMNACYP1A2 | |
| SCHEMBL30097224 | 0.82 | EGFR (0.42) | PRMT1EGFRMAPK1LMNACYP1A2 | |
| SCHEMBL27410545 | 0.82 | EGFR (0.42) | PRMT1EGFRMAPK1LMNACYP1A2 | |
| SCHEMBL27409290 | 0.81 | AURKA (0.40) | PRMT1EGFRMAPK1LMNACYP1A2 | |
| SCHEMBL30097159 | 0.81 | AURKA (0.40) | PRMT1EGFRMAPK1LMNACYP1A2 | |
| SCHEMBL27409242 | 0.81 | AURKA (0.40) | PRMT1EGFRMAPK1LMNACYP1A2 | |
| SCHEMBL30097205 | 0.80 | PRMT1 (0.38) | PRMT1EGFRMAPK1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022197734-A1 | BICYCLIC HETEROARYL BORONATE DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | RIBOSCIENCE LLC (US) | 2022-09-22 | — | — | WO | disclosed |