Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 19/20 | 0.76 |
| ▸ | HTR2B | P41595 | 18/20 | 0.76 |
| ▸ | HTR2A | P28223 | 18/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300639 | 0.91 | HTR2C (0.70) | HTR2CHTR2BHTR2A | |
| SCHEMBL183797 | 0.86 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL183660 | 0.84 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL183604 | 0.81 | HTR2A (0.81) | HTR2CHTR2BHTR2A | |
| SCHEMBL300930 | 0.80 | HTR2A (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL183789 | 0.79 | HTR2A (1.00) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL183749 | 0.79 | HTR2A (0.98) | HTR2CHTR2BHTR2A | |
| SCHEMBL183736 | 0.78 | HTR2C (0.85) | HTR2CHTR2BHTR2A | |
| SCHEMBL183657 | 0.78 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL183458 | 0.77 | HTR2C (0.84) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928461-B1 | PYRIMIDINE COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-01-04 | — | — | EP | claimed |