Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23413305 | 1.00 | MAPT (0.46) | MAPTPOLBGAAGPBAR1SIRT2 | |
| SCHEMBL23413303 | 0.87 | GPBAR1 (0.40) | MAPTPOLBGPBAR1SIRT2PLAU | |
| SCHEMBL30097629 | 0.87 | GPBAR1 (0.40) | MAPTPOLBGPBAR1SIRT2PLAU | |
| SCHEMBL30097509 | 0.86 | MAPT (0.46) | MAPTPOLBGAASIRT2PLAU | |
| SCHEMBL23413197 | 0.86 | MAPT (0.46) | MAPTPOLBGAASIRT2PLAU | |
| SCHEMBL23412641 | 0.85 | MAPT (0.46) | MAPTGAAGPBAR1KMT2ASMN1; SMN2 | |
| SCHEMBL30097572 | 0.85 | MAPT (0.46) | MAPTGAAGPBAR1KMT2ASMN1; SMN2 | |
| SCHEMBL23413500 | 0.84 | GAA (0.44) | MAPTPOLBGAASIRT2PLAU | |
| SCHEMBL23413189 | 0.80 | GPBAR1 (0.55) | MAPTPOLBGPBAR1PLAUKMT2A | |
| SCHEMBL30097697 | 0.80 | GPBAR1 (0.55) | MAPTPOLBGPBAR1PLAUKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115348959-B | Heteroaryl compounds and their therapeutic use in conditions associated with altered beta-glucocerebrosidase activity | GT增益治疗股份有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-115348959-A | Heteroaryl compounds and their therapeutic use in disorders associated with altered beta-glucocerebrosidase activity | 增益治疗股份有限公司 | 2022-11-15 | — | — | CN | disclosed |