Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 9/20 | 0.40 |
| ▸ | TAB1 | Q15750 | 9/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619829 | 1.00 | CYP2A6 (0.43) | CYP2A6LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4695073 | 0.88 | MAP3K7 (0.42) | CYP2A6LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1006461 | 0.83 | CYP2A6 (0.56) | CYP2A6LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31167180 | 0.83 | CYP2A6 (0.56) | CYP2A6LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12636082 | 0.77 | CYP2A6 (0.41) | CYP2A6MAP3K7TAB1GAAKDM4E | |
| SCHEMBL658960 | 0.77 | AXL (0.42) | CYP2A6AXLMAP3K7TAB1IMPDH2 | |
| SCHEMBL23022152 | 0.75 | CYP2A6 (0.43) | CYP2A6EP300KAT2BKAT8MAP3K7 | |
| SCHEMBL23021840 | 0.75 | CYP2A6 (0.40) | CYP2A6MAP3K7TAB1KDM4EALDH1A1 | |
| SCHEMBL3931535 | 0.75 | CYP2A6 (0.41) | CYP2A6CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL8881790 | 0.71 | CYP2A6 (0.51) | CYP2A6GAAKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878514-A | Heterocyclic compounds for modulating NR2F6 | TES制药有限责任公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-115427394-A | Heterocyclic compounds for modulating NR2F6 | TES制药有限责任公司 | 2022-12-02 | — | — | CN | disclosed |