Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.47 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479997 | 1.00 | DPP4 (0.49) | DPP4DPP8DPP9FOLH1NAALAD2 | |
| SCHEMBL30099605 | 1.00 | DPP4 (0.49) | DPP4DPP8DPP9FOLH1NAALAD2 | |
| SCHEMBL30099703 | 1.00 | DPP4 (0.49) | DPP4DPP8DPP9FOLH1NAALAD2 | |
| SCHEMBL30099555 | 1.00 | DPP4 (0.49) | DPP4DPP8DPP9FOLH1NAALAD2 | |
| SCHEMBL30099442 | 1.00 | DPP4 (0.49) | DPP4DPP8DPP9FOLH1NAALAD2 | |
| SCHEMBL30099592 | 1.00 | DPP4 (0.49) | DPP4DPP8DPP9FOLH1NAALAD2 | |
| SCHEMBL30312227 | 0.98 | DPP4 (0.50) | DPP4DPP8DPP9FOLH1NAALAD2 | |
| SCHEMBL31266941 | 0.96 | DPP4 (0.46) | DPP4DPP8DPP9FOLH1NAALAD2 | |
| SCHEMBL29886770 | 0.95 | FOLH1 (0.53) | DPP4DPP8DPP9FOLH1NAALAD2 | |
| SCHEMBL30193226 | 0.95 | FOLH1 (0.53) | DPP4DPP8DPP9FOLH1NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250123280-A1 | LABEL-FREE DETECTION OF PROTEASE ACTIVITY | UNIV OREGON HEALTH & SCIENCE (US) | 2025-04-17 | — | — | US | claimed |
| WO-2023003984-A2 | LABEL-FREE DETECTION OF PROTEASE ACTIVITY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-01-26 | — | — | WO | claimed |
| US-20250188139-A1 | VEGF-C MUTEINS FOR SELECTIVE LYMPHATIC STIMULATION | YALE UNIVERSITY (US) | 2025-06-12 | — | — | US | disclosed |
| US-20250123280-A1 | LABEL-FREE DETECTION OF PROTEASE ACTIVITY | UNIV OREGON HEALTH & SCIENCE (US) | 2025-04-17 | — | — | US | disclosed |
| CN-119522235-A | VEGF-C muteins for selective lymphatic stimulation | 耶鲁大学 | 2025-02-25 | — | — | CN | disclosed |
| EP-4490175-A2 | VEGF-C MUTEINS FOR SELECTIVE LYMPHATIC STIMULATION | Yale University (US) | 2025-01-15 | — | — | EP | disclosed |
| WO-2024168252-A2 | USE OF INHIBITORS OF VEGF-C SIGNALING FOR INHIBITING IMMUNE RESPONSES AND INCREASING GENE THERAPY EFFICACY | YALE UNIVERSITY (US) | 2024-08-15 | — | — | WO | disclosed |
| WO-2023172964-A2 | VEGF-C MUTEINS FOR SELECTIVE LYMPHATIC STIMULATION | YALE UNIVERSITY (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2023003984-A2 | LABEL-FREE DETECTION OF PROTEASE ACTIVITY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-01-26 | — | — | WO | disclosed |