Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.43 |
| ▸ | NMUR1 | Q9HB89 | 5/20 | 0.43 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.43 |
| ▸ | RAMP3 | O60896 | 6/20 | 0.41 |
| ▸ | CALCR | P30988 | 6/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30978864 | 0.92 | MAPK8 (0.49) | MAPK8MAPK9MAPK10KEAP1NMUR2 | |
| SCHEMBL30099574 | 0.87 | NMUR2 (0.49) | NMUR2NMUR1NAA50RAMP3CALCR | |
| SCHEMBL31031577 | 0.87 | KDM1A (0.45) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL30925881 | 0.86 | MAPK8 (0.47) | MAPK8MAPK9MAPK10KEAP1NMUR2 | |
| SCHEMBL30925880 | 0.86 | MAPK8 (0.47) | MAPK8MAPK9MAPK10KEAP1NMUR2 | |
| SCHEMBL29753847 | 0.86 | MAPK8 (0.49) | MAPK8MAPK9MAPK10KEAP1NMUR2 | |
| SCHEMBL29837332 | 0.86 | MAPK8 (0.49) | MAPK8MAPK9MAPK10KEAP1NMUR2 | |
| SCHEMBL30099619 | 0.86 | MC4R (0.45) | NMUR2NMUR1NAA50RAMP3CALCR | |
| SCHEMBL29825310 | 0.85 | MAPK8 (0.44) | MAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL31165809 | 0.85 | MAPK8 (0.45) | MAPK8MAPK9MAPK10KEAP1NMUR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023003984-A2 | LABEL-FREE DETECTION OF PROTEASE ACTIVITY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-01-26 | — | — | WO | claimed |