Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FADS1 | O60427 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | LYN | P07948 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23675409 | 1.00 | P2RX1 (0.56) | P2RX1MEN1KMT2AFADS1L3MBTL1 | |
| SCHEMBL26096971 | 0.90 | P2RX1 (0.59) | P2RX1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL26099973 | 0.88 | MEN1 (0.54) | P2RX1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL23675410 | 0.86 | KDM4C (0.57) | P2RX1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL30100505 | 0.86 | KDM4C (0.57) | P2RX1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL23675418 | 0.86 | P2RX1 (0.62) | P2RX1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL23675429 | 0.86 | TMPRSS4 (0.57) | P2RX1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL30100434 | 0.86 | TMPRSS4 (0.57) | P2RX1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL30100456 | 0.86 | MEN1 (0.49) | P2RX1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL23675430 | 0.86 | MEN1 (0.49) | P2RX1MEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093401-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | The Board of Regents of the University of Texas System (US) | 2022-11-30 | — | — | EP | disclosed |