Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.66 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.59 |
| ▸ | BRD2 | P25440 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593649 | 1.00 | BRD4 (0.66) | BRD4CREBBPBRD2 | |
| SCHEMBL3599751 | 0.86 | BRD4 (0.59) | BRD4CREBBPBRD2 | |
| SCHEMBL434040 | 0.81 | BRD4 (0.68) | BRD4CREBBPBRD2 | |
| SCHEMBL1771061 | 0.79 | BRD4 (1.00) | BRD4CREBBPBRD2 | |
| SCHEMBL20160389 | 0.79 | BRD4 (0.66) | BRD4CREBBPBRD2 | |
| SCHEMBL8134588 | 0.79 | BRD4 (0.66) | BRD4CREBBPBRD2 | |
| SCHEMBL3593647 | 0.79 | BRD4 (0.66) | BRD4CREBBPBRD2 | |
| SCHEMBL22513821 | 0.77 | BRD4 (0.62) | BRD4CREBBPBRD2 | |
| SCHEMBL2054633 | 0.77 | BRD4 (0.62) | BRD4CREBBPBRD2 | |
| SCHEMBL1770806 | 0.77 | BRD4 (0.62) | BRD4CREBBPBRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093400-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | The Trustees of Princeton University (US) | 2022-11-30 | — | — | EP | disclosed |