SCHEMBL30100880

SCHEMBL30100880

C=C(c1ccc([SiH](C)C)cc1)c1cccc([Si](CC)(CC)OCC)c1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 2/20 0.31
PDE4B Q07343 2/20 0.31
PDE4C Q08493 2/20 0.31
PDE4D Q08499 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28921891 1.00 PDE4A (0.31) PDE4APDE4BPDE4CPDE4D
SCHEMBL30100862 0.89 PDE4A (0.32) PDE4APDE4BPDE4CPDE4D
SCHEMBL28921899 0.89 PDE4A (0.32) PDE4APDE4BPDE4CPDE4D
SCHEMBL30132063 0.87 MEN1 (0.36) PDE4APDE4BPDE4CPDE4D
SCHEMBL28935393 0.87 MEN1 (0.36) PDE4APDE4BPDE4CPDE4D
SCHEMBL30100853 0.86 PDE4A (0.34) PDE4APDE4BPDE4CPDE4D
SCHEMBL28921879 0.86 PDE4A (0.34) PDE4APDE4BPDE4CPDE4D
SCHEMBL28921865 0.85
SCHEMBL30100861 0.85
SCHEMBL28615429 0.77 MEN1 (0.42) PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115536762-B Liquid crystal grafted modified polystyrene with wide liquid crystal temperature range, differential photoresponse and reversible isomerization and preparation method thereof 大连理工大学 2024-06-14 CN claimed
CN-115536762-A Differential photoresponse and isomerization reversible liquid crystal grafted modified polystyrene with wide liquid crystal temperature domain and preparation method thereof 大连理工大学 2022-12-30 CN claimed
CN-115536762-B Liquid crystal grafted modified polystyrene with wide liquid crystal temperature range, differential photoresponse and reversible isomerization and preparation method thereof 大连理工大学 2024-06-14 CN disclosed
CN-115536762-A Differential photoresponse and isomerization reversible liquid crystal grafted modified polystyrene with wide liquid crystal temperature domain and preparation method thereof 大连理工大学 2022-12-30 CN disclosed