Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 11/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28559463 | 0.81 | TAAR1 (0.55) | TAAR1HTR1ADRD2HTR7RAB9A | |
| SCHEMBL30101003 | 0.81 | TAAR1 (0.51) | TAAR1HTR1ADRD2HTR7RAB9A | |
| SCHEMBL19674426 | 0.77 | TAAR1 (0.48) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL28515741 | 0.73 | TAAR1 (0.60) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL28515743 | 0.73 | TAAR1 (0.60) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL19674229 | 0.72 | TAAR1 (0.46) | TAAR1HTR1ADRD2HTR7 | |
| Ulotaront SCHEMBL21273313 | 0.71 | TAAR1 (0.76) | TAAR1HTR1ADRD2HTR7ALDH1A1 | |
| SCHEMBL18723730 | 0.71 | TAAR1 (0.57) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL20964261 | 0.71 | TAAR1 (0.57) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL14906850 | 0.71 | TAAR1 (0.57) | TAAR1HTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433205-A | Polycyclic derivative receptor agonist, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-12-06 | — | — | CN | disclosed |