Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 16/20 | 0.86 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.86 |
| ▸ | FGFR1 | P11362 | 12/20 | 0.57 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | BTK | Q06187 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27188441 | 1.00 | FGFR4 (0.86) | FGFR4FGFR2FGFR1FGFR3KDR | |
| SCHEMBL27188437 | 1.00 | FGFR4 (0.86) | FGFR4FGFR2FGFR1FGFR3KDR | |
| SCHEMBL27188387 | 0.94 | FGFR4 (0.76) | FGFR4FGFR2FGFR1FGFR3KDR | |
| SCHEMBL30101139 | 0.94 | FGFR4 (0.76) | FGFR4FGFR2FGFR1FGFR3KDR | |
| SCHEMBL27188458 | 0.91 | FGFR4 (0.71) | FGFR4FGFR2FGFR1FGFR3KDR | |
| SCHEMBL27188456 | 0.91 | FGFR4 (0.71) | FGFR4FGFR2FGFR1FGFR3KDR | |
| SCHEMBL30516033 | 0.89 | FGFR4 (0.69) | FGFR4FGFR2FGFR1FGFR3KDR | |
| SCHEMBL30101130 | 0.88 | FGFR4 (0.68) | FGFR4FGFR2FGFR1FGFR3BTK | |
| SCHEMBL27188377 | 0.88 | FGFR4 (0.68) | FGFR4FGFR2FGFR1FGFR3BTK | |
| SCHEMBL27188370 | 0.88 | FGFR4 (0.68) | FGFR4FGFR2FGFR1FGFR3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433190-A | Preparation method and application of irreversible heterocyclic compound FGFR inhibitor | 药雅科技(上海)有限公司 | 2022-12-06 | — | — | CN | disclosed |