Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123511 | 1.00 | PCSK9 (0.61) | PCSK9KDM4EMEN1GAAKMT2A | |
| SCHEMBL30101689 | 0.90 | PCSK9 (0.64) | PCSK9KDM4EMEN1GAAKMT2A | |
| SCHEMBL29123682 | 0.90 | PCSK9 (0.64) | PCSK9KDM4EMEN1GAAKMT2A | |
| SCHEMBL29123656 | 0.87 | PCSK9 (0.62) | PCSK9KDM4EMEN1GAAKMT2A | |
| SCHEMBL30101616 | 0.87 | PCSK9 (0.62) | PCSK9KDM4EMEN1GAAKMT2A | |
| SCHEMBL29123691 | 0.85 | PCSK9 (0.76) | PCSK9KDM4EMEN1GAAKMT2A | |
| SCHEMBL30101758 | 0.85 | PCSK9 (0.76) | PCSK9KDM4EMEN1GAAKMT2A | |
| SCHEMBL30101699 | 0.84 | PCSK9 (0.70) | PCSK9KDM4EMEN1GAAKMT2A | |
| SCHEMBL29123519 | 0.84 | PCSK9 (0.70) | PCSK9KDM4EMEN1GAAKMT2A | |
| SCHEMBL29123613 | 0.83 | KDM4E (0.62) | PCSK9KDM4EMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109011-B | Benzothiazole compound, preparation method and application | 河北师范大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-115109011-A | Benzothiazole compound, preparation method and application | 河北师范大学 | 2022-09-27 | — | — | CN | disclosed |