Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSD | A5PKW4 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23390221 | 1.00 | PSD (0.40) | PSDCYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL23390225 | 1.00 | PSD (0.40) | PSDCYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL23950594 | 0.99 | PSD (0.40) | PSDCYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL23950756 | 0.97 | PSD (0.41) | PSDCYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL30101939 | 0.97 | PSD (0.41) | PSDCYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL23390302 | 0.93 | CYP2A6 (0.39) | CYP3A4CYP2C9CYP2C19ADORA2AADORA1 | |
| SCHEMBL23390306 | 0.93 | CYP2A6 (0.39) | CYP3A4CYP2C9CYP2C19ADORA2AADORA1 | |
| SCHEMBL23390503 | 0.92 | CYP2A6 (0.37) | CYP3A4CYP2C9CYP2C19ADORA2AADORA1 | |
| SCHEMBL23390500 | 0.92 | CYP2A6 (0.37) | CYP3A4CYP2C9CYP2C19ADORA2AADORA1 | |
| SCHEMBL26878141 | 0.92 | ADORA2A (0.36) | CYP3A4CYP2C9CYP2C19ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | claimed |
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | disclosed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |