Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 13/20 | 0.36 |
| ▸ | MYLK | Q15746 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23950769 | 1.00 | CYP2A6 (0.39) | CYP2A6KCNH2CLK1DYRK1APIM1 | |
| SCHEMBL23925582 | 1.00 | CYP2A6 (0.39) | CYP2A6KCNH2CLK1DYRK1APIM1 | |
| SCHEMBL25463141 | 0.93 | CLK1 (0.38) | KCNH2CLK1DYRK1APIM1MYLK | |
| SCHEMBL23950535 | 0.93 | CLK1 (0.38) | KCNH2CLK1DYRK1APIM1MYLK | |
| SCHEMBL23950537 | 0.93 | CLK1 (0.38) | KCNH2CLK1DYRK1APIM1MYLK | |
| SCHEMBL23950752 | 0.90 | CLK1 (0.41) | CYP2A6KCNH2CLK1DYRK1APIM1 | |
| SCHEMBL23925494 | 0.90 | CLK1 (0.41) | CYP2A6KCNH2CLK1DYRK1APIM1 | |
| SCHEMBL23925639 | 0.88 | CLK1 (0.36) | KCNH2CLK1DYRK1APIM1PIK3CA | |
| SCHEMBL23950604 | 0.88 | CLK1 (0.36) | KCNH2CLK1DYRK1APIM1PIK3CA | |
| SCHEMBL23950991 | 0.88 | KCNH2 (0.38) | KCNH2CLK1DYRK1APIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | claimed |
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | disclosed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |