Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.59 |
| ▸ | ACVR1 | Q04771 | 5/20 | 0.48 |
| ▸ | TEK | Q02763 | 3/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KDM4B | O94953 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058328 | 0.78 | PDE2A (0.47) | PARP1COMT | |
| SCHEMBL1360723 | 0.78 | PARP1 (0.77) | PARP1ACVR1IP6K1CHEK1PIM1 | |
| SCHEMBL29966835 | 0.75 | PARP1 (1.00) | PARP1TEKKDM4AKDM4BKDM5C | |
| SCHEMBL4619270 | 0.75 | PARP1 (1.00) | PARP1TEKKDM4AKDM4BKDM5C | |
| SCHEMBL31718112 | 0.74 | PARP1 (0.58) | PARP1ACVR1TEKIP6K1CHEK1 | |
| SCHEMBL31058347 | 0.73 | PARP1 (0.68) | PARP1ACVR1TEKKDM4AKDM4B | |
| SCHEMBL23950529 | 0.71 | PIM1 (0.45) | PARP1PIM1 | |
| SCHEMBL30101918 | 0.71 | PIM1 (0.45) | PARP1PIM1 | |
| SCHEMBL30683274 | 0.70 | PARP1 (0.49) | PARP1ACVR1TEKKDM4AKDM4B | |
| SCHEMBL869256 | 0.70 | PARP1 (0.59) | PARP1ACVR1KDM4AKDM4BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | disclosed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |