Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28651874 | 1.00 | KMT2A (0.64) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL28651876 | 1.00 | KMT2A (0.64) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL20626808 | 0.93 | KMT2A (0.63) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL20626809 | 0.93 | KMT2A (0.63) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL18065735 | 0.85 | KMT2A (0.52) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL4850919 | 0.85 | KMT2A (0.61) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL4083264 | 0.83 | NPC1 (0.48) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL9659260 | 0.82 | KMT2A (0.53) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL9659264 | 0.82 | KMT2A (0.53) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL4851282 | 0.82 | KMT2A (0.53) | KMT2ANPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480485-B | 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof | 甘肃农业大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-111978201-B | Synthesis method of N, N' -diaryl benzoyl hydrazine compound | 甘肃农业大学 | 2023-01-03 | — | — | CN | disclosed |