SCHEMBL30102207

SCHEMBL30102207

Cc1cccc(N=Nc2cccc(C)c2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.67
KMT2A Q03164 7/20 0.67
NPC1 O15118 7/20 0.67
RAB9A P51151 5/20 0.67
CASP3 P42574 3/20 0.67
SENP8 Q96LD8 3/20 0.67
SENP7 Q9BQF6 3/20 0.67
SENP6 Q9GZR1 3/20 0.67
TDP1 Q9NUW8 2/20 0.67
NSD2 O96028 1/20 0.67
ACHE P22303 3/20 0.58
HTR3E A5X5Y0 2/20 0.58
HTR3B O95264 2/20 0.58
HTR3A P46098 2/20 0.58
HTR3D Q70Z44 2/20 0.58
HTR3C Q8WXA8 2/20 0.58
MAPT P10636 6/20 0.55
POLB P06746 1/20 0.55
GFER P55789 1/20 0.55
ESR1 P03372 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11981455 1.00 MEN1 (0.67) MEN1KMT2ANPC1RAB9ACASP3
SCHEMBL1405327 1.00 MEN1 (0.67) MEN1KMT2ANPC1RAB9ACASP3
SCHEMBL30332449 1.00 MEN1 (0.67) MEN1KMT2ANPC1RAB9ACASP3
SCHEMBL1405329 1.00 MEN1 (0.67) MEN1KMT2ANPC1RAB9ACASP3
SCHEMBL1405502 0.93 MEN1 (0.66) MEN1KMT2ANPC1RAB9ACASP3
SCHEMBL30540401 0.93 MEN1 (0.66) MEN1KMT2ANPC1RAB9ACASP3
SCHEMBL10818345 0.93 MEN1 (0.60) MEN1KMT2ANPC1RAB9ACASP3
SCHEMBL1405503 0.93 MEN1 (0.66) MEN1KMT2ANPC1RAB9ACASP3
SCHEMBL10814151 0.91 NPC1 (0.69) MEN1KMT2ANPC1RAB9ACASP3
SCHEMBL30471681 0.91 NPC1 (0.69) MEN1KMT2ANPC1RAB9ACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117623941-A Preparation method of high-quality 4,4 '-diamino-2, 2' -dimethylbiphenyl 天津众泰材料科技有限公司 2024-03-01 CN disclosed
CN-113480485-B 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof 甘肃农业大学 2023-04-07 CN disclosed
CN-111978201-B Synthesis method of N, N' -diaryl benzoyl hydrazine compound 甘肃农业大学 2023-01-03 CN disclosed