Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAT1 | O14929 | 4/20 | 0.61 |
| ▸ | RBBP7 | Q16576 | 4/20 | 0.61 |
| ▸ | KAT7 | O95251 | 1/20 | 0.61 |
| ▸ | EP300 | Q09472 | 1/20 | 0.61 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | USP2 | O75604 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | CASP7 | P55210 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TST | Q16762 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30102423 | 0.91 | HAT1 (0.70) | HAT1RBBP7KAT7EP300CREBBP | |
| Trifluoroacetic Acid SCHEMBL863616 | 0.86 | MEN1 (0.64) | HAT1RBBP7KAT7EP300CREBBP | |
| SCHEMBL30102443 | 0.83 | HAT1 (0.70) | HAT1RBBP7KAT7EP300CREBBP | |
| SCHEMBL30102477 | 0.81 | MEN1 (0.74) | HAT1RBBP7KAT7EP300CREBBP | |
| SCHEMBL30102401 | 0.80 | HAT1 (0.64) | HAT1RBBP7KAT7EP300CREBBP | |
| SCHEMBL30102396 | 0.78 | HAT1 (0.61) | HAT1RBBP7KAT7EP300CREBBP | |
| SCHEMBL24806063 | 0.78 | HAT1 (0.64) | HAT1RBBP7KAT7EP300CREBBP | |
| SCHEMBL30102513 | 0.78 | HAT1 (0.78) | HAT1RBBP7KAT7EP300CREBBP | |
| SCHEMBL864193 | 0.76 | MEN1 (0.69) | HAT1RBBP7KAT7EP300CREBBP | |
| SCHEMBL24805257 | 0.76 | HAT1 (1.00) | HAT1RBBP7KAT7EP300CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188083-A1 | Modulators of Histone Acetyltransferase 1 and Methods of Treatment Thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-06-12 | — | — | US | disclosed |
| WO-2022272313-A1 | MODULATORS OF HISTONE ACETYLTRANSFERASE 1 AND METHODS OF TREATMENT THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250188083-A1 | Modulators of Histone Acetyltransferase 1 and Methods of Treatment Thereof | EP300, HDAC1, NAT1 | HAT1 8/4885RBBP7 69/4885KAT7 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.