Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723517 | 1.00 | TRPV1 (0.58) | TRPV1SMN1; SMN2GAAMEN1TP53 | |
| SCHEMBL2724621 | 0.89 | TRPV1 (0.62) | TRPV1SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL31679061 | 0.87 | TRPV1 (0.66) | TRPV1SMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL2725222 | 0.87 | TRPV1 (0.66) | TRPV1SMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL31679069 | 0.86 | TRPV1 (0.59) | TRPV1SMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL2725244 | 0.86 | TRPV1 (0.59) | TRPV1SMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL2724882 | 0.85 | TRPV1 (0.58) | TRPV1SMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL2723627 | 0.85 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL2724955 | 0.85 | TRPV1 (0.58) | TRPV1SMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL2724894 | 0.85 | TRPV1 (0.67) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3393462-B1 | COMPOSITIONS AND METHODS FOR TREATMENT, AMELIORATION, AND PREVENTION OF ANESTHESIA-INDUCED HYPOTHERMIA | UNIV ARIZONA (US) | 2023-02-01 | — | — | EP | claimed |