Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 1.00 |
| ▸ | BCL2 | P10415 | 3/20 | 0.69 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3010261 | 1.00 | BCL2L1 (1.00) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL2997201 | 0.95 | BCL2L1 (1.00) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL2997198 | 0.95 | BCL2L1 (1.00) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL3006878 | 0.95 | BCL2L1 (1.00) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL3006876 | 0.95 | BCL2L1 (1.00) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL3011152 | 0.88 | BCL2L1 (0.78) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL3011157 | 0.88 | BCL2L1 (0.78) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL3001094 | 0.88 | BCL2L1 (1.00) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL3001117 | 0.88 | BCL2L1 (1.00) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL3009340 | 0.86 | BCL2L1 (1.00) | BCL2L1BCL2BCL2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197711-A1 | BENZOTHIAZOLE COMPOUNDS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2010-08-05 | — | — | US | disclosed |
| EP-2193127-A1 | BENZOTHIAZOLE COMPOUNDS | The Walter and Eliza Hall Institute of Medical Research (AU) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009039553-A1 | BENZOTHIAZOLE COMPOUNDS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2009-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197711-A1 | BENZOTHIAZOLE COMPOUNDS | BAD, BCL2, BAX | BCL2L1 4/4885BCL2 2/4885BCL2L2 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.