Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103141 | 0.88 | KDM1A (0.42) | PDGFRBPDGFRACYP17A1HPGDSFYN | |
| SCHEMBL24785077 | 0.88 | KDM1A (0.42) | PDGFRBPDGFRACYP17A1HPGDSFYN | |
| SCHEMBL24785367 | 0.85 | PDGFRB (0.51) | PDGFRBPDGFRACYP17A1ALDH1A1RAB9A | |
| SCHEMBL2860140 | 0.83 | PDGFRB (0.55) | PDGFRBPDGFRACYP17A1ALDH1A1RAB9A | |
| SCHEMBL30103108 | 0.83 | CYP17A1 (0.50) | PDGFRBPDGFRACYP17A1ALDH1A1RAB9A | |
| SCHEMBL24785848 | 0.83 | CYP17A1 (0.50) | PDGFRBPDGFRACYP17A1ALDH1A1RAB9A | |
| SCHEMBL9815140 | 0.80 | RARB (0.52) | PDGFRBPDGFRACYP17A1ALDH1A1RAB9A | |
| SCHEMBL9815142 | 0.80 | RARB (0.52) | PDGFRBPDGFRACYP17A1ALDH1A1RAB9A | |
| SCHEMBL19876623 | 0.78 | PDGFRB (0.55) | PDGFRBPDGFRACYP17A1ALDH1A1RAB9A | |
| SCHEMBL30103109 | 0.76 | PDGFRB (0.48) | PDGFRBPDGFRACYP17A1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |