Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.64 |
| ▸ | CA2 | P00918 | 11/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26424218 | 1.00 | CA1 (0.64) | CA1CA2GPBAR1MAPTMEN1 | |
| SCHEMBL26424224 | 1.00 | CA1 (0.64) | CA1CA2GPBAR1MAPTMEN1 | |
| SCHEMBL26426560 | 0.94 | CA1 (0.59) | CA1CA2GPBAR1MAPTMEN1 | |
| SCHEMBL23704682 | 0.93 | GPBAR1 (0.60) | CA1CA2GPBAR1MAPTMEN1 | |
| SCHEMBL23704681 | 0.93 | GPBAR1 (0.60) | CA1CA2GPBAR1MAPTMEN1 | |
| SCHEMBL23710363 | 0.93 | CA1 (0.65) | CA1CA2GPBAR1MAPTMEN1 | |
| SCHEMBL30103321 | 0.93 | CA1 (0.65) | CA1CA2GPBAR1MAPTMEN1 | |
| SCHEMBL26424097 | 0.92 | CA1 (0.64) | CA1CA2GPBAR1MAPTMEN1 | |
| SCHEMBL30103327 | 0.92 | CA1 (0.59) | CA1CA2GPBAR1MAPTMEN1 | |
| SCHEMBL26426837 | 0.92 | CA1 (0.59) | CA1CA2GPBAR1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097119-B1 | BILE ACID-GCPII INHIBITOR CONJUGATES TO TREAT INFLAMMATORY DISEASES | UNIV JOHNS HOPKINS (US) | 2025-05-07 | — | — | EP | disclosed |
| EP-4097119-A1 | BILE ACID-GCPII INHIBITOR CONJUGATES TO TREAT INFLAMMATORY DISEASES | The Johns Hopkins University (US) | 2022-12-07 | — | — | EP | disclosed |