Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.62 |
| ▸ | HTR2A | P28223 | 9/20 | 0.62 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13208414 | 0.85 | HTR2A (0.62) | HTR2CHTR2AHTR3AKCNH2 | |
| SCHEMBL4705406 | 0.80 | HTR2A (0.68) | HTR2CHTR2ASIGMAR1KCNH2 | |
| SCHEMBL3155248 | 0.79 | HTR2C (0.69) | HTR2CHTR2AKCNH2 | |
| SCHEMBL5917403 | 0.77 | HTR2A (0.68) | HTR2CHTR2AMAPT | |
| SCHEMBL4705400 | 0.77 | HTR2A (0.68) | HTR2CHTR2AADRB1SIGMAR1MEN1 | |
| SCHEMBL5917499 | 0.77 | HTR2C (1.00) | HTR2CHTR2AADRB1HTR3EHTR3B | |
| SCHEMBL6714516 | 0.77 | HTR2C (0.55) | HTR2CHTR2AHTR1DADRB1HTR3E | |
| Hydrochloric Acid SCHEMBL5917431 | 0.76 | HTR2C (0.97) | HTR2CHTR2AHTR3EHTR3BHTR3A | |
| SCHEMBL2356686 | 0.74 | HTR2A (1.00) | HTR2CHTR2AHTR3EHTR3BHTR3A | |
| SCHEMBL24640538 | 0.74 | HTR2C (0.42) | HTR2CHTR2AHTR1DADRB1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022247839-A1 | PARP7 INHIBITOR | 山东轩竹医药科技有限公司 | 2022-12-01 | — | — | WO | disclosed |