Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 3/20 | 0.47 |
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831665 | 1.00 | EPHX2 (0.47) | EPHX2KDRBRAFGAASMN1; SMN2 | |
| SCHEMBL23831680 | 0.89 | EPHX2 (0.49) | EPHX2KDRBRAFGAAHTT | |
| SCHEMBL30105250 | 0.89 | EPHX2 (0.49) | EPHX2KDRBRAFGAAHTT | |
| SCHEMBL30105056 | 0.87 | EPHX2 (0.43) | EPHX2SMN1; SMN2HTTMAPTNPC1 | |
| SCHEMBL23831765 | 0.87 | EPHX2 (0.43) | EPHX2SMN1; SMN2HTTMAPTNPC1 | |
| SCHEMBL23831771 | 0.86 | MAPT (0.56) | SMN1; SMN2HTTMAPTALDH1A1TSHR | |
| SCHEMBL23832088 | 0.84 | EPHX2 (0.49) | EPHX2KDRBRAFGAAHTT | |
| SCHEMBL30105123 | 0.84 | EPHX2 (0.49) | EPHX2KDRBRAFGAAHTT | |
| SCHEMBL23831927 | 0.83 | EPHX2 (0.39) | EPHX2KDRSMN1; SMN2HTTMAPT | |
| SCHEMBL23831757 | 0.83 | EPHX2 (0.46) | EPHX2SMN1; SMN2HTTMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |