Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831627 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2HTTNPC1RAB9AGRIK1 | |
| SCHEMBL23831617 | 0.92 | TRPV1 (0.39) | SMN1; SMN2HTTNPC1RAB9AGRIK1 | |
| SCHEMBL30104967 | 0.92 | TRPV1 (0.39) | SMN1; SMN2HTTNPC1RAB9AGRIK1 | |
| SCHEMBL30105182 | 0.91 | MAPT (0.42) | SMN1; SMN2HTTNPC1RAB9AGRIK1 | |
| SCHEMBL23831831 | 0.91 | MAPT (0.42) | SMN1; SMN2HTTNPC1RAB9AGRIK1 | |
| SCHEMBL23831819 | 0.91 | SMN1; SMN2 (0.40) | SMN1; SMN2HTTNPC1RAB9AGRIK1 | |
| SCHEMBL30105233 | 0.91 | SMN1; SMN2 (0.40) | SMN1; SMN2HTTNPC1RAB9AGRIK1 | |
| SCHEMBL23831791 | 0.90 | GRIK1 (0.42) | SMN1; SMN2HTTNPC1RAB9AGRIK1 | |
| SCHEMBL30105260 | 0.90 | GRIK1 (0.42) | SMN1; SMN2HTTNPC1RAB9AGRIK1 | |
| SCHEMBL23831729 | 0.90 | HTT (0.43) | SMN1; SMN2HTTNPC1RAB9AGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |