Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 7/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 4/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832115 | 1.00 | MEN1 (0.49) | MEN1KMT2AGRIK1TRPV1KCNH2 | |
| SCHEMBL30105107 | 0.91 | MEN1 (0.47) | MEN1KMT2AGRIK1TRPV1KCNH2 | |
| SCHEMBL23831737 | 0.91 | MEN1 (0.47) | MEN1KMT2AGRIK1TRPV1KCNH2 | |
| SCHEMBL30104987 | 0.88 | SMARCA2 (0.58) | MEN1KMT2AGRIK1TRPV1SMARCA2 | |
| SCHEMBL23831586 | 0.88 | HTT (0.48) | MEN1KMT2ATRPV1LMNAMAPT | |
| SCHEMBL30105228 | 0.88 | HTT (0.48) | MEN1KMT2ATRPV1LMNAMAPT | |
| SCHEMBL23831732 | 0.88 | SMARCA2 (0.58) | MEN1KMT2AGRIK1TRPV1SMARCA2 | |
| SCHEMBL23831798 | 0.86 | MEN1 (0.49) | MEN1KMT2AGRIK1TRPV1MAPT | |
| SCHEMBL23832117 | 0.85 | KMT2A (0.44) | MEN1KMT2AGRIK1TRPV1KCNH2 | |
| SCHEMBL23831894 | 0.85 | GRIK1 (0.52) | MEN1KMT2AGRIK1TRPV1SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |