Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831969 | 0.93 | TRPV1 (0.49) | TRPV1PTGER3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30105158 | 0.93 | TRPV1 (0.49) | TRPV1PTGER3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30105124 | 0.93 | PTGER3 (0.48) | TRPV1PTGER3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23831658 | 0.93 | PTGER3 (0.48) | TRPV1PTGER3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30104912 | 0.89 | TRPV1 (0.51) | TRPV1PTGER3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23831810 | 0.89 | TRPV1 (0.51) | TRPV1PTGER3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23831943 | 0.88 | TRPV1 (0.53) | TRPV1PTGER3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30104965 | 0.88 | TRPV1 (0.53) | TRPV1PTGER3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23832072 | 0.88 | TRPV1 (0.52) | TRPV1PTGER3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30104950 | 0.88 | TRPV1 (0.52) | TRPV1PTGER3CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-B1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIV PALACKEHO (CZ) | 2024-02-07 | — | — | EP | disclosed |
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |