Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MARS1 | P56192 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831808 | 1.00 | GRIK1 (0.65) | GRIK1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL23831915 | 0.90 | MEN1 (0.63) | GRIK1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL30104966 | 0.90 | MEN1 (0.63) | GRIK1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL30105181 | 0.90 | GRIK1 (0.67) | GRIK1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL23831763 | 0.90 | GRIK1 (0.67) | GRIK1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL23831816 | 0.90 | MEN1 (0.60) | GRIK1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL30105034 | 0.90 | MEN1 (0.62) | GRIK1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL23831843 | 0.90 | MEN1 (0.62) | GRIK1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL23831914 | 0.89 | GRIK1 (0.49) | GRIK1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL23831827 | 0.86 | GRIK1 (0.47) | GRIK1MEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |