Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.37 |
| ▸ | RAB9A | P51151 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831860 | 1.00 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23831958 | 0.93 | CNR1 (0.40) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL30105113 | 0.93 | CNR1 (0.40) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL30104964 | 0.92 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23831685 | 0.92 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23832061 | 0.90 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL30105084 | 0.90 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23831633 | 0.89 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL30104995 | 0.89 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23831669 | 0.88 | CNR1 (0.44) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |