Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831587 | 1.00 | GRIK1 (0.43) | GRIK1MEN1KMT2ACA12CA1 | |
| SCHEMBL30105213 | 0.93 | GRIK1 (0.44) | GRIK1MEN1KMT2ACA12CA1 | |
| SCHEMBL23831891 | 0.93 | GRIK1 (0.44) | GRIK1MEN1KMT2ACA12CA1 | |
| SCHEMBL30105111 | 0.92 | GRIK1 (0.51) | GRIK1MEN1KMT2ACA12CA1 | |
| SCHEMBL27077631 | 0.92 | GRIK1 (0.51) | GRIK1MEN1KMT2ACA12CA1 | |
| SCHEMBL23832012 | 0.91 | MAPT (0.42) | GRIK1MEN1KMT2ACA12CA1 | |
| SCHEMBL23831721 | 0.91 | TRPV1 (0.43) | GRIK1MEN1KMT2ACA12CA1 | |
| SCHEMBL30105345 | 0.91 | TRPV1 (0.43) | GRIK1MEN1KMT2ACA12CA1 | |
| SCHEMBL30105120 | 0.91 | MAPT (0.42) | GRIK1MEN1KMT2ACA12CA1 | |
| SCHEMBL23831702 | 0.90 | GRIK1 (0.45) | GRIK1MEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |