Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831849 | 1.00 | MEN1 (0.63) | MEN1KMT2AMAPTRAB9AMTOR | |
| SCHEMBL30105237 | 0.89 | GRIK1 (0.57) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL30105244 | 0.89 | MEN1 (0.66) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL30105181 | 0.89 | GRIK1 (0.67) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL23831763 | 0.89 | GRIK1 (0.67) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL23831975 | 0.89 | MEN1 (0.66) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL23831672 | 0.89 | GRIK1 (0.57) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL23831939 | 0.89 | MEN1 (0.57) | MEN1KMT2AMAPTRAB9AMTOR | |
| SCHEMBL23831816 | 0.89 | MEN1 (0.60) | MEN1KMT2AMAPTRAB9AMTOR | |
| SCHEMBL23831937 | 0.89 | MEN1 (0.80) | MEN1KMT2AMAPTRAB9AMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-B1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIV PALACKEHO (CZ) | 2024-02-07 | — | — | EP | disclosed |
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |