Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MARS1 | P56192 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831684 | 1.00 | MEN1 (0.58) | MEN1KMT2ARAB9AGRIK1TRPV1 | |
| SCHEMBL23831646 | 0.90 | MEN1 (0.60) | MEN1KMT2ARAB9AGRIK1TRPV1 | |
| SCHEMBL30105090 | 0.90 | MEN1 (0.60) | MEN1KMT2ARAB9AGRIK1TRPV1 | |
| SCHEMBL30104989 | 0.89 | KMT2A (0.59) | MEN1KMT2ARAB9AGRIK1TRPV1 | |
| SCHEMBL23831770 | 0.89 | KMT2A (0.59) | MEN1KMT2ARAB9AGRIK1TRPV1 | |
| SCHEMBL23831708 | 0.88 | TRPV1 (0.59) | MEN1KMT2ARAB9AGRIK1TRPV1 | |
| SCHEMBL30105275 | 0.88 | TRPV1 (0.59) | MEN1KMT2ARAB9AGRIK1TRPV1 | |
| SCHEMBL23831866 | 0.88 | TRPV1 (0.45) | MEN1KMT2ARAB9AGRIK1TRPV1 | |
| SCHEMBL23832041 | 0.86 | TRPV1 (0.44) | MEN1KMT2ARAB9AGRIK1TRPV1 | |
| SCHEMBL30105328 | 0.86 | TRPV1 (0.44) | MEN1KMT2ARAB9AGRIK1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-B1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIV PALACKEHO (CZ) | 2024-02-07 | — | — | EP | disclosed |
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |