Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.56 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27077601 | 1.00 | SMARCA2 (0.56) | SMARCA2SMARCA4KMT2AGRIK1MEN1 | |
| SCHEMBL23831732 | 0.88 | SMARCA2 (0.58) | SMARCA2SMARCA4KMT2AGRIK1MEN1 | |
| SCHEMBL30104987 | 0.88 | SMARCA2 (0.58) | SMARCA2SMARCA4KMT2AGRIK1MEN1 | |
| SCHEMBL30105297 | 0.88 | KMT2A (0.46) | SMARCA2SMARCA4KMT2AGRIK1MEN1 | |
| SCHEMBL23831934 | 0.88 | KMT2A (0.46) | SMARCA2SMARCA4KMT2AGRIK1MEN1 | |
| SCHEMBL23831598 | 0.86 | S1PR2 (0.55) | KMT2AGRIK1MEN1HTTKDM4E | |
| SCHEMBL23831709 | 0.85 | SMARCA2 (0.56) | SMARCA2SMARCA4KMT2AMEN1HTT | |
| SCHEMBL30105088 | 0.85 | KMT2A (0.44) | SMARCA2SMARCA4KMT2AGRIK1MEN1 | |
| SCHEMBL23832117 | 0.85 | KMT2A (0.44) | SMARCA2SMARCA4KMT2AGRIK1MEN1 | |
| SCHEMBL30105045 | 0.85 | SMARCA2 (0.56) | SMARCA2SMARCA4KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |